Review of the Histology of the
Integumentary System

Divisions of the Integumentary System
Functions
Epidermis
    notes
    Strata
    Melanocytes
Dermis
    notes
    layers of dermis
    Meissner corpuscle
Hypodermis
Accessory Structures
    sebaceous gland
    sweat gland
    hair
    hair follicle
    arrector pili muscle

Functions:
1. protection of underlying tissues
2. temperature regulation
3. excretion
         urea and uric acid in sweat
4. Synthesizes vitamin D with UV light
5. Communication

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Epidermis

General Characteristics of the epidermis
1. Most superficial layer of the skin
2. Stratified squamous epithelium
3. No vascularization

Layers of the epidermis
1. Stratum basale/germinativum (red arrow in picture below)
     a. deepest layer of the epidermis;  lies on the upper portion of the dermis
      b. gets adequate nourishment from under lying vascular tissue in the dermis
      c. this layer contains stem cells that divide and produce the more superficial layers as daughter cells are pushed toward the
            surface
      d. one layer of columnar or cuboidal shaped cells
2. Stratum spinosum (light blue bracket)
     a. superficial to the stratum basal and deep to the stratum granulosum
        b. gets adequate nourishment from under lying vascular tissue in the dermis
        c. in older slide preparations the cells would appear spiky
        d.  more division occurs here
 3. Stratum granulosum (green arrow)
      a. three to 5 layers of cells superficial to the stratum spinosum
       b. cells are flattened and appear as a dark band
      c. in the upper border of this layer the cells are beginning to die & organelles are deteriorating
      d. the cytoplasm is filling with granules
               i. lamellated granules
                    contributes to waterproofing
               ii. keratohyaline granules
                    form keratin fibrils
                    contributes to toughness
4. Stratum lucidum (black arrow)
    a. clear layer
    b. has mostly keratinocytes
    c. only present in thick skin
5. Stratum corneum (dark blue bracket)
     a. "horny layer"
     b. most superficial 20-30 cell layers
     c. makes up most of the thickness of the epidermis
     d. cells are dead and flattened
     e. this layer is being rubbed off and replaced

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Epidermis
Photo by Dr. S. Desai

Stratum basale/germinativum (indicated by the red arrow)
Stratum spinosum (indicated by the light blue bracket)
Stratum granulosum (indicated by the green arrow)
Stratum lucidum (indicated by the black arrow)
Stratum corneum (indicated by the dark blue bracket)

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Melanocytes
1. found in the stratum basale
2. produce melanin pigments that shade the nuclei of dividing cells from UV light

Photo by Dr. W. Coons

You can see the melanin in the melanocytes in the stratum basale (indicated by the green arrow).

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Dermis

Layers of the dermis
1. Papillary layer
     a. Most superficial layer of the dermis
       b. Has lots of areolar CT
       c. Dermal papillae
            i. uneven "nipple" like projections
            ii. responsible for fingerprints
       d. Has lots of capillary networks
      e. Contains pain and touch receptors
2. Reticular layer
     a. The deepest layer of the dermis
       b. Characterized by lots of dense irregular CT
            (mostly collagen fibers for strength with a few elastin fibers for elasticity)
       c. Contains many arteries and veins, sweat and sebaceous glands and pressure receptors
       d. This layer looks much more "messy" than the pappilary layer

Photo taken by Dr. W. Coons
Dermis
The black bracket indicates the papillary layer and the blue bracket indicates the reticular layer of the dermis. (100x)

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Meissner Corpuscle
The blue arrow and brackets indicate a Meissner corpuscle at different magnifications.  The photos on the left are unlabeled so you can see the structure without any visual distractions.

Photo taken by Dr. W. Coons

Meissner corpuscle in a dermal papillae at 100x

Photo taken by Dr. W. Coons

Meissner corpuscle in a dermal papillae at 200x

Photo taken by Dr. W. Coons

Meissner corpuscle in a dermal papillae at 400x

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Accessory organs
1. Hair
2. Follicle:  invagination of epidermis and dermis that accommodates the hair
3. Arrector pili muscle:smooth muscle moves hair and is responsible for "goose bumps"
4. Cutaneous Glands
     a. Sebaceous glands
          i. all over the skin, except the palms of the hands and the soles of the feet
          ii. usually empty into a hair follicle
          iii. secretes sebum
               + oil and fragmented cells
               + lubricant to keep skin soft and moist
               + keeps hair from getting brittle
     b. Sweat glands
          i. distributed all over skin
          ii. pores
          iii. Two types
                + Eccrine glands
                        -found almost all over
                        -secretes mostly water, salts and urea
                  + Apocrine glands
                        -found in axillary and pubic regions
                                       -secretes protein and fat rich substances
                        -BO
Photo taken by Dr. W. Coons

The green arrows indicate the follicle.  The blue arrow is pointing to a sebaceous gland.

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Photo taken by Dr. W. Coons

Black arrow-hair;  blue arrow -arrector pili muscle; green circle - sweat glands;  green arrow - sebaceous gland

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Hypodermis
1. adipose tissue
2. anchors skin to underlying organs
3. shock absorber and insulation
4. mature shape
 

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Designed and constructed by
M. E. Janowski-Bell, Ph.D.
Assistant Professor of Biology
Victoria College
tarantula@victoriacollege.edu